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ABOUT PI

I am a veterinarian; I hold a position as an assistant professor in colleague of medicine at Chang Gung University. I obtained my bachelor’s and Master’s degrees in Veterinary Medicine from National Taiwan University. I have another clinical master’s degree in Veterinary Clinical Medicine specialized in avian pathology from Ecole Nationale Vétérinaire d’Alfort, France. I received my PhD in Animal Genetics from the Institut National Agronomique Paris-Grignon in France. Before joining Chang Gung University, I was a researcher at French National Center for Scientific Research (CNRS) and at Pasteur Institute, Paris, where I received my training to work in biosafety level 3 laboratories (P3), and I was in charge of a research program on influenza viruses in wild birds. The Research Center for Emerging Viral Infections which contains several biosafety level 2 laboratories (P2 plus) at Chang Gung University was designed by me due to my experiences from Pasteur Institute. My major research areas are: emerging and re-emerging viral infections, genomics, molecular genetics, zoonotic diseases, international collaboration, and international innovation and entrepreneurship.

I have a very broad international contact network especially with European countries because I speak fluently both French and English. I was the project leader of a Taiwan-Czech bilateral research project during 2010 to 2012. I was the co-investigator of the Health National Contact Point, Taiwan, of EU Framework Program from 2011 to 2013. From 2014 to 2016, I was the co-investigator of a French-Taiwan ANR project. From 2019 August, I become the Chief Executive Officer at Chang Gung university of the Global Research & Industry Alliance (GLORIA), Ministry of Science and Technology, Taiwan. I am in charge of setting international collaborative programs between Chang-Gung University and EU/French partners. I am also now the president of the l’Association Franco-Taiwanais des échanges academiques, culturels, et  économiques. Outside the laboratory and the classroom, I enjoy spending time with my family, traveling and tasting Taiwan and French cuisine.

        張中明是法國動物遺傳學博士,也是具有豐富臨床經驗的小動物及禽病臨床獸醫師。目前在臺灣長庚大學醫學生物技術暨檢驗學系任專任助理教授; 長庚大學動物中心首席獸醫師,同時於臺灣大學獸醫專業學院獸醫學系任兼任助理教授。張中明博士除了有執業臨床獸醫師的實務經驗外,亦具備下列基礎學科與跨領域基因體學之學術專長,目前主要研究領域是動物分子遺傳學、分子病毒流行病學、基因體學、人畜共通傳染病,實驗動物及經濟動物獸醫學,生物科技產學合作及國際合作等範疇

 

1. 動物遺傳學、基因體學、生物醫學、分子生物學及分子醫學 : 專長於病毒學、流行病學、基因體學及分子遺傳學之診斷醫學。具優良的新興病毒學、醫學生物和分子生物技術,還有血清學和免疫學診斷技術及細胞培養技術等。

2. 實驗動物及經濟動物獸醫學 : 具動物遺傳學博士學位、國家獸醫師執照、現任長庚大學動物中心首席獸醫師、台大家畜醫院兼任住院醫師經歷。專精於小動物疾病之預防診斷和治療,小動物外科操作,實驗動物管理。並取得法國專業臨床禽病獸醫師證書,專精於禽病學,同時具備臨床及基礎研究能力。

3. 人畜共通傳染病、高等生物安全實驗室設計、操作及管理: 在法國巴斯德研究所接受完整高等安全生物實驗室設計、操作及管理的訓練,更有在第三級高等生物安全實驗室(P3)操作過高病源性禽流感病毒(H5N1)的實際經驗。

4. 生物科技產學合作及國際合作: 擔任歐盟科研架構計畫主題國家聯絡據點團隊計畫,健康領域主題國家聯絡據點之共同計畫主持人 和國內外的生物科技學術和產業界有良好和密切的接觸, 有利用奈米和光電生物科技結合醫學的臨床應用經驗。

 


        張中明助理教授於過去的研究發現和確定了雞的羽毛隱性白突變和雞的內源性反轉錄病毒插入是完全相關的。其重要應用是於法國高經濟價值的紅標土雞的分子育種選拔,造福和確保了法國紅標土雞對養殖業者的品質與經濟效益。同時也開設了自營品牌「張醫師的開心農場」,並同時專注於生態及病毒流行病學研究。另一研究為人類內源性反轉錄病毒和自體免疫疾病及癌症之相關研究。張中明助理教授是長庚大學新興病毒感染研究中心與法國及歐洲多個的國際研究中心國國際合作的起始者之一。過去與曾主持國科會台灣-捷克雙邊合作計畫,利用高通量的定序技術以及生物資訊學方法,進行癌症與人類內源性反轉錄病毒的相關研究。除了專注於研究及授課之外,張中明助理教授也很享受與家人的相處時光、旅行以及享受法式美食。

E-mail: cmchang@mail.cgu.edu.tw ; chungming.chang@gmail.com

Webpage : http://cmclabtw.wixsite.com/cmclab

Co-investigator, EU FP7, Health National Contact Point Taiwan

http://sites.mc.ntu.edu.tw/project/health_en_ncp

Diploma and License

Virology and Human Molecular Genetics

Emerging and re-emerging viral infections

Recent research topic

Avian Influenza: Diagnostic, epidemiology and phylogeny study of Avian Influenza of wild birds.

Human endogenous retrovirus:

1. Copy number and insertional polymorphism study of human endogenous retrovirus HERV-K in rheumatoid arthritis patients

2. Functional analysis of endogenous retroviral elements in human genome: possible association withcancers (NGS)

Animal Genetics, Biodiversity

Molecular Genetics:

RT-PCR, Quantitative RT-PCR, gene sequencing and analysis, gene cloning, Southern Blot, Western Blot, DNA hybridisation, Restriction Fragment Length Polymorphism.

Avian Pathology

Prevention, diagnostic and treatment of poultry diseases.

Virology: virus isolation from egg-passages and identification of virus serotype. 

Serology and immunology: HA, HI, IFA, ELISA.

Cell culture: primary cell culture from the chicken embryo.

Bimolecular techniques: gene sequencing and analysis, PCR, DNA hybridization.

Laboratory animals, Pets

Disease control and prevention, diagnostic, treatment and animal reproduction.

Laboratory and small animal diseases, clinical practice and surgical operation.

06/02/2006

PhD Degree in Animal Genetics Institut National Agronomique

Paris-Grignon, France

Thesis: Molecular genetics of colouration in chickens: study of the tyrosinase gene and identification of the molecular bases of the ‘recessive white’ mutation

Advisor: Doctor Michèle TIXIER-BOICHARD

2002 - 2003

Certificate of French writing level II Institut Catholique de Paris

07/1999

Certificat d’Etudes Supérieures de Pathologie Aviaire, 3ème cycle Ecole Nationale Vétérinaire d’Alfort, France

Mémoire: Infectious bronchitis and its importance in Taiwan

Advisor: Professor Jeanne BRUGERE-PICOUX

1996 - 1998

Master’s Degree of Veterinary Medicine National Taiwan University, Taiwan

Thesis: Analysis of the Genome of a Pigeon Adenovirus and Establishment of a Diagnostic System

Advisor: Professor Ching-Ho WANG

09/1996

National License of Doctor Veterinary Medicine, Taiwan

Doctor of Veterinary Medicine

1992 - 1996

National Taiwan University, Taiwan

Bachelor’s Degree of Veterinary Medicine

Areas of Expertise

Languages

Chinese Mandarin and Taiwanese: Native language

English: Fluent

 

French: Fluent

 

Spanish: Beginner

Experience

From 2007/8/1          

Assistant Professor. Department of Medical Biotechnology and Laboratory Science Chang Gung University, Taiwan

 

2006 – 2007

Researcher (Ingenieur de Recherche) in Institut Pasteur and Centre national de la recherche scientifique (CNRS) in France

 

2001 – 2002

French learning in Paris

 

1999 – 2001

Military service. Sergeant of Republic of China army (Taiwan)

 

1996 – 1998

Doctor Veterinary Medicine: Private clinic – Harvard Animal Hospital

 

1996 – 1997

Doctor Veterinary Medicine: Animal Hospital of National Taiwan University

 

1992 – 1994

Research Technician National Taiwan University, Avian Pathology Research Unit & Poultry Association Republic of China (Taiwan)

Award and Honors

Aquatic Pollutants Joint transnational call 2020-2021. European project consortium member.

Invited grant proposal reviewer for the National Science Center, Poland, 2020

Chief Executive Officer at Chang Gung university of the Global Research & Industry Alliance (GLORIA), Ministry of Science and Technology, Taiwan, from August 2019.

Chief Executive Officer at Chang Gung university of the Global Research & Industry Alliance (GLORIA), Ministry of Science and Technology, Taiwan, from August 2019.

Invited Project reviewer of Canadian Poultry Research Council, 2016

Project evaluator of Ministry of Science and Technology from 2014 to present.

Committee member of Animal medicine, Bureau of Animal and Plant Health Inspection and Quarantine, Council of  Agriculture, Executive Yuan,  2014 to 2016

Expert Reviewer

Grant proposal reviewer for the National Science Center 2020

Clinica Chimica Acta 2021~2013

 

Clinica Chimica Acta 2012

Clinica Chimica Acta 2011

Journal of Pest Science 2011

International Journal of Infectious Diseases 2010

Clinica Chimica Acta 2010

Microbes and Infection 2010

Animal Genetics 2009

Biology Letters 2009

Antarctic Science 2007

Animal Genetics 2007

Veterinary Microbiology 2006

Expert Reviewer

Czech part:

Project leader, Chung-Ming CHANG, DVM, PhD, Assistant professor, National Science Council of Taiwan, (grant 99-2923-B-182-001-MY3), from 2010, Institute of Molecular Genetics, Academy of Sciences, Czech Republic and Research Center for Emerging Viral Infections, Chang Gung University, Taiwan

Project title: Functional analysis of endogenous retroviral elements in human genome: possible association with cancers

 

French part:

Co-project leader, Chung-Ming CHANG, DVM, PhD, Assistant professor, Orchid project 2008-2009; Pasteur Institute-Chang Gung University;

Project leader: Shih Shin-Ru, PhD, Professor and Director, Research Center for Emerging Viral Infections, Chang Gung University, Taiwan

Project title: Identification and functional study of amino acid co-variation on the RNA polymerase, nucleoprotein and matrix protein of influenza A viruses

 

Co-project leader, Chung-Ming CHANG, DVM, PhD, Assistant professor, King Penguin research; Animal Health Research Institute, Chang Gung University and Fondation Tour du Valat, 2008

Project leader: Tsenz chun-shein, DVM. Dr. Researcher at Animal Health Research Institute, Taiwan

Project title: Study of correlation between Wildlife Diseases and human activities based on viral diseases investigation of King Penguins (Aptenodytes patagonicus)

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